PTCA guide wires (Micro wires) are designed to navigate vessels to reach a lesion. guide wires are indicated to facilitate the placement of balloon dilatation catheters during percutaneous transluminal coronary angioplasty (PTCA). Wires are characterized by their pushability, flexibility, steerability, torque and opacity. Guide wires are basically made of Solid steel or nitinol core wires and solid core wire wrapped in a smaller wire coil or braid. Coiled or braided wires offer a large amount of flexibility, pushability and kink resistance. wires are coated with a polytetrafluoroethylene (PTFE), to increase lubricity. Hydrophilic coatings reduce friction during deployment and for easier movement in tortuous vessels.